Am J Cardiovasc Dis 2011;1(3):227-235

Review Article
Anatomo-functional characterization of interatrial septum for catheter-based

Gianluca Rigatelli , Beatrice Magro, Laura Oliva

Section of Congenital Heart Disease Interventions, Cardiovascular Diagnosis and Endoluminal
Interventions Unit, Rovigo General Hospital, Rovigo, Italy

Received July 7, 2011; accepted July 27, 2011; Epub August 10, 2011; published September 30, 2011

Abstract: Secundum Atrial septal defect (ASD) and Patent foramen ovale (PFO) are becoming the most popular field of
interest for catheter-based interventions. While there is a common agreement about the management of ASD patients,
there is no complete agreement on which is the best management of PFO  patients. In PFO patients, the real challenge for
the clinician, beside secondary prevention of recurrent stroke, is to understand which are the higher risk patients to refer for
treatment and which is the proper device to use.  In this setting, the anatomo-functional characterization of interatrial  
septum seems to be of paramount importance for both ASD and PFO, not only for the device selection  but also for
therapeutic decision-making. In the present review the author overviews the main anatomic an functional characteristics of
interatrial septum, obtained with the current available diagnostic tools, such as transcranial doppler, transthoracic and
transesophageal echocardiography and intracardiac echocardiography, and  discusses the impact of such characteristics
on catheter based closure. (AJCD1107005).


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